NeutroCure – Methodology

Specific microenvironment is established under disease conditions: for example, elevated levels of ROS are present in cancer cells and tumors as well as in aberrant polymorphonuclear neutrophils (PMN’s) in infammatory and autoimmune diseases.

Nuclei staining: DAPI. ROS staining: MitoSOX
NeutroCure will make use of these differences between pathological and normal states to develop safe ROS-amplifiers targeting aberrant PMN’s. These amplifiers can be potentially used for treatment of inflammatory and autoimmune diseases, cancer and myeloablation.